Data Analysis Tools for DNA Microarrays

Sorin Draghici

Publisher: Chapman & Hall /CRC Press

ISBN: 1584883154

Order from Chapman & Hall /CRC Press.

Related Research.


 

Corrections:

1. Chapter 3, Image Processing

Pg. 40 Diagram has a typo,

"red cha       l"

should be read as

"red channel".

2. Chapter 4, Elements of Statistics

Pg 99; top of the page, equation 4.64

" E[Z] " should be read as " E[Z2] ".

3. Chapter 5, Statistical Hypothesis Testing

Pg. 128; Equation 5.25

P(Z>=1.8) = 1 - P(Z<=1.8)

should be read as

P(Z>1.8) = 1 - P(Z<=1.8)

4. Chapter 6, Classical Approaches to data analysis

Pg 129; the middle of the page was 

"According to the first ..........different types of problem that can arise."

should be read as

"According to the first ..........different types of problems that can arise."

Pg. 131; Second paragraph in the first line

"8 measurements"

should be read as

"9 measurements"

Pg. 133; Example 6.1, step 4

'n' should be substituted as '9' and not '8' .

Pg 135; the second line from bottom of the page was 

"However, the two conditions (α = 0.05 and β = 0.95) ..."

should be read as

"However, the two conditions (α = 0.01 and β = 0.05) ...".

5. Chapter 7, Analysis of Variance - ANOVA

Pg 175; the third equation on the page was 

SS Blocks  =  k T2.j  -  T2.. /N  = 212.44

should be read as

SS Blocks  =  j T2.j / K  -  T2.. / N  = 212.44

Pg 177; the first equation on the page was 

SS Blocks  =  k T2.j  -  T2.. /N  = 1162.44

should be read as

SS Blocks  =  j T2.j / K  -  T2.. / N  = 1162.44

Pg 177; the results after the equation (7.51) were

F2,10(1.16) = 0.009

F5,10(0.56) = 0.015

should be read as

F2,10(6.45) = 0.009

F5,10(5.75) = 0.015

6. Chapter 9, Multiple Comparisons

Pg 221; the sentence towards the end of the page was

"For instance a small array with 5,000 genes on .......is expected to produce 500 false positives ......"

should be read as

"For instance a small array with 5,000 genes on .......is expected to produce 50 false positives ......"

Pg 225; 1st line, 2nd paragraph,

"FRD" should be read as "FDR".

Pg 228; towards the bottom,

C36 = (63) = (6.5.4)/(3.2.1) = 20

should be read as

3P6 = 6.5.4 = 120

Pg 228; towards the bottom,

C612 = (126) = (12.11.10.9.8.7)/(6.5.4.3.2.1) = 924

should be read as

6P12 = 12.11.10.9.8.7 = 665280

7. Chapter 10, Analysis of Visualization Tools

Pg 234; second sentence on the second paragraph

"Fig. 12.4 presents a scatter plot ....."

should be read as

"Fig. 10.4 presents a scatter plot .....".

8. Chapter 11, Cluster Analysis

Pg 279; the sentence at about half-way down the page was

"It follows that the membership or any particular gene to any particular cluster...."

should be read as

"It follows that the membership of any particular gene to any particular cluster...."

9. Chapter 12, Data pre-processing and normalization

Pg 332; equation 12.20

SMi = Tbi(log2(PMi,j) -log2(MMi,j)

should be read as

SBi = Tbi(log2(PMi,j) -log2(MMi,j))

10. Chapter 13, Methods for selecting differentially regulated genes

Pg 343; middle of the page

"Example 4.6 in Chap. 4 showed that a diagnosis method with the specificity of 90% ..."

should be read as

"Example 4.6 in Chap. 4 showed that a diagnosis method with the sensitivity of 90% ..."

Pg 355; middle of the second paragraph

"The placement of the two graphs corresponds to our expectation: the maximum probability (the peak of the pdf) for unexpressed genes is lower than the maximum probability for the expressed genes."

should be read as

"The placement of the two graphs corresponds to our expectation: the maximum probability (the peak of the pdf) for unexpressed genes is at a lower intensity than the intensity corresponding to the maximum probability for the expressed genes."

11. Chapter 15, Focused microarrays - comparison and selection

Pg 385; Section 15.2, last sentence of the second last paragraph

"Onto-Compare is a to"

must be ignored.

12. Chapter 16, Commercial applications

Pg 412; third paragraph, sentences from  2nd sentence onwards are repeated.

"Once the data have been imported, ......... ,intensity dependent location  normalization using the loess function."

should be ignored.


Dr. Sorin Draghici
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